Meet the Team

Realizing the Promise of AI in the Clinic

March 6, 2020

The gap between the development of AI and its use and integration in the clinic is closing, as technology, sophisticated algorithms, data sets, and computational capacity are now directly supporting both clinicians and patient care in clinical settings. Yet, realizing the full impact of AI for patient care and improved diagnostic decision making will depend…

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tayabba hasan, phd

From the Lab to the Clinic: Hasan Ready to Translate Her Photodynamic Research Into Patient Care

February 19, 2020

After nearly four decades of developing light-based technologies for treating disease at Massachusetts General Hospital (MGH), Tayyaba Hasan, PhD is excited about the potential to turn her discoveries into new treatments for patients. “We’re at a good place scientifically with this light-triggered nanotechnology, where the light is an agent that provides something unique,” Hasan says.…

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Keith Joung, MD, PhD

Driving CRISPR to the Clinic

February 21, 2019

In the short time since the emergence of CRISPR gene editing technology, Keith Joung, MD, PhD has been impressed with all the research applications that have been developed to harness its potential. “It is remarkable how it’s been used to build cell lines and model organisms, gain new insights into more of the mechanisms of…

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Calum MacRae, MD, PhD

Calum MacRae, MD, PhD: One Brave Heart

January 10, 2017

Musing over the proposal that netted him a $75 million “One Brave Idea” prize from the American Heart Association, Calum MacRae, MD, PhD recognizing the many applicants for the grant, credits good luck and strong collaborations over ingenuity. “I think the funders were brave to give us the money.” Nevertheless, MacRae, chief of cardiovascular medicine…

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Connecting Care

October 13, 2016

Keeping track of personal health has become an industry. From off-the-shelf fitness trackers and mobile apps to systematic efforts like the quantified-self movement, personal health monitoring is virtually ubiquitous. Yet long before it became commonplace, Partners Connected Health sought to change the approach to health care delivery: from provider-driven treatment to patient-centered care. Launched twenty…

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Gary Ruvkun, PhD: MicroRNA, Cancer and Heart Disease

January 12, 2016

As a child growing up in the Sputnik era, Gary Ruvkun, PhD explored the night skies through the lens of a telescope and, as he learned more astronomy, realized with fascination that the universe has secret layers. “When you do visible astronomy, you see one set of stars. When you do X-ray as-tronomy, you see…

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Stephen Elledge, PhD Wins Lasker Award

September 1, 2015

A profile of BWH's Lasker Award winning Stephen Elledge, PhD and a look at his work on eukaryotic DNA damage response, as well as a new focus on the mechanisms of cell cycle control. In some ways, the eukaryotic cell is akin to a miniature city: Mitochondrial energy plants power the cell; lysosomes act as…

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Innovator Profile: Innovation's Building Blocks

April 1, 2015

A profile of Charles Serhan, PhD, DSc, a mastermind behind the inflammation pro-resolving therapies known as resolvins and the specialized pro-resolving mediators (SPM). Charles Serhan, PhD, DSc, a mastermind behind the inflammation pro-resolving therapies known as resolvins and the specialized pro-resolving mediators (SPM), is no stranger to the celebrity side of science. Coming of age…

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The Austen Family: Lifetimes of Innovation and Healing

December 1, 2014

Highlighting the Austens, a family whose innovations have revolutionized medical care and clinical research since the 1950s. For a fortunate few, vision isn't just one of the five senses. It's the predominant sense; it's a way of life. Vision is imagining a solution, already attained: What does it look like? How does it work? Where…

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Investigator Profile: Warren Zapol, MD and Nitric Oxide

May 1, 2014

A profile of Warren Zapol, MD, the Emeritus Anesthetist-in-Chief and Reginald Jenney Professor of Anesthesia at Harvard Medical School In the 25 years since discovering a life-saving therapy consisting of breathing low levels of the gas nitric oxide—which is still the only selective inhaled pulmonary vasodilator—Massachusetts General Hospital (MGH) anesthesiologist Warren M. Zapol, MD, and…

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Dieter Manstein MD, PhD: Innovative Procedures Get Under Your Skin

December 1, 2013

A profile of Dieter Manstein, MD, PhD, and his great achievements in Dermatology: fractional photothermolysis and selective Cryolipolysis®. Dieter Manstein, MD, PhD turned a two-year research project into a career of developing major dermatology innovations to treat scars, skin aging, and noninvasively remove fat. In November of 1998, he immigrated to Boston, from Germany, where…

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Richard Lee, MD: Fighting Aging One Beat at a Time

December 1, 2013

A look at Richard Lee, MD's research and discovery of GDF11 aimed at aging in the heart. When two prominent researchers meet for coffee, you never know what breakthrough medical advances might arise. Five years ago, Richard Lee, MD, a cardiologist at Brigham and Women's Hospital, and his good friend Harvard regenerative biologist Amy Wagers,…

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Technology Profile: Studies Awakening New Understanding of Anesthesia

December 1, 2013

Emery Brown, MD, PhD, and Patrick Purdon, PhD give insight into their research and use of a new neuroscience-based approach to researching anesthesia. A few years ago, Emery Brown, MD, PhD, realized that something seemingly obvious was missing from the way anesthesiologists historically had approached their research since drugs were first used to induce general…

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